Biochemical blockade of cholinergic thirst

Tolerance for quinine under cholinergic versus deprivation induced thirst.

Cholinergic blockade and tonic immobility in chickens

To investigate the effects of cholinergic blockade on duration of tonic immobility (TI) and habituation to handling and the TI testing procedure, two groups of cockerel chicks were tested following injection with scopolamine or saline. One week later half of each group was given a second test for TI following injection with saline or scopolamine. Results indicated that scopolamine significantly...

Personalized genetics of the cholinergic blockade of neuroinflammation

Acetylcholine signaling is essential for cognitive functioning and blocks inflammation. To maintain homeostasis, cholinergic signaling is subjected to multi-leveled and bidirectional regulation by both proteins and non-coding microRNAs ('CholinomiRs'). CholinomiRs coordinate the cognitive and inflammatory aspects of cholinergic signaling by targeting major cholinergic transcripts including the ...

Cholinergic blockade in the prevention of exercise-induced asthma.

The contribution of vagal mechanisms to exercise-induced asthma has been studied in 10 adult asthmatic patients using the anticholinergic drug ipratropium bromide. Exercise tests were performed for eight minutes on a cycle ergometer and each individual's tests were standardised by matching oxygen uptake. Two tests were done on each of three study days, the first being without previous medicatio...

Thirst

hypothermia is an adjunct, purely a "metabolic crutch, providing additional time in which to pursue the specific treatment, whether medical or surgical." The pathophysiology of the major congenital and acquired cardiac lesions is discussed in terms of the applicability and usefulness of hypothermia. In addition, the author discusses and evaluates the varied clinical situations in which hypother...